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From Despair to Delivery Room: A Patient's Journey at Metro IVF

Success Tips | 31 Mar 2026

From Despair to Delivery Room: A Patient's Journey at Metro IVF

This is the story of one woman's journey. It is told in her voice — reconstructed from conversations, clinical records, and the account she gave us permission to share — because the voice of a patient who has lived this experience carries a truth that no clinical description can fully replicate.

Her name, for this telling, is Sarita. She is from a small town in Koriya district, Chhattisgarh. She is thirty-seven years old. She has a daughter who will turn one in three months.

This is how she got there.


Part One: The Years Before

Sarita married at twenty-six. She had always assumed, with the casual confidence of someone who had never had reason to think otherwise, that children would come when she and her husband Deepak decided to have them. There was no family history of fertility problems. There were no warning signs. There was nothing that suggested the decade that followed would be what it was.

The first year of trying passed without a pregnancy. The second year began the cycle of consultations — a local gynecologist first, then a clinic in Bilaspur, then a hospital in Raipur. Tests were performed. Hormonal profiles were drawn. Semen analyses were conducted. Everything, at each clinic, came back within normal limits. The diagnosis, repeated with small variations in language across three different clinics over five years, was the same: unexplained infertility.

Sarita described the experience of receiving this diagnosis, repeatedly, as a particular kind of invisible wound. The word unexplained, she said, felt like a door being closed without anyone having looked behind it properly. It meant: we have done our standard tests, and they are normal, and we cannot tell you why this is not happening. It did not mean: we have looked everywhere. It meant: we have looked where we always look.

IVF was recommended in her sixth year of trying. She underwent two cycles — one at the Raipur clinic, one at a clinic in Nagpur to which she and Deepak traveled specifically because it had been recommended by someone they trusted. The Raipur cycle produced two embryos. Neither implanted. The Nagpur cycle produced three embryos — grade A blastocysts, the embryologist had said, with a confidence that had felt, in retrospect, like a promise that the biology did not keep. None implanted.

After the Nagpur cycle, Sarita said, something changed in her. Not the desire — the desire had not changed. But the relationship between the desire and the daily life she was living had shifted. The hope had gone underground. She described herself, in that period, as functioning normally from the outside while carrying something very heavy from the inside. Getting up, going to work, managing the house, smiling at relatives during festivals, deflecting questions with the practiced ease of someone who has been deflecting them for years. And underneath all of it, a grief that had no proper name because the thing she was grieving — a child who did not exist, a future that had not arrived — was not something that other people recognized as a loss in the way they would recognize a death.

That was where she was when her neighbor mentioned Metro IVF.


Part Two: The Phone Call She Almost Did Not Make

The neighbor's mention was casual — the name of a clinic in Ambikapur, a doctor she had heard about from someone in her family who knew a couple from Surguja whose situation had sounded similar to Sarita's. Not a referral. Not a recommendation with specific clinical knowledge behind it. Just a name, offered gently into the space of a conversation that had touched, briefly, on what Sarita was going through.

Sarita did not call Metro IVF for three weeks after that conversation.

She described the delay as a form of self-protection. She had, by that point, invested hope in three clinics and two IVF cycles, and the aftermath of each investment — the particular emotional cost of hoping and then absorbing a failure — had accumulated into something that made the prospect of investing again feel genuinely dangerous. One more appointment, she told herself, was one more opportunity for a result that would take months to recover from.

Deepak was the one who eventually made the call — quietly, without telling Sarita until the appointment was booked. His reasoning, which he shared with her over dinner on the evening he told her, was simple: he was not ready to accept that they had tried everything if there was a clinic they had not visited, a doctor they had not spoken to. The consultation was not a commitment to another cycle. It was a conversation.

Sarita agreed to go.


Part Three: The Consultation That Changed Everything

They drove to Ambikapur on a Tuesday morning in November — a three-hour drive from their town in Koriya, through the forest roads of northern Chhattisgarh, arriving at Metro IVF with the quiet wariness of people who have learned not to expect too much from an appointment.

The waiting room was modest. The clinical environment was professional and clean without being intimidating. And when they were called in, Dr. Ashish Soni did something that Sarita had not experienced in a decade of fertility consultations.

He asked them to tell him everything, from the beginning. And then he listened.

Not with the half-attention of a doctor building a diagnosis while a patient is still speaking. He listened with what Sarita described as complete presence — asking questions that showed he had understood what she said before, returning to details she had mentioned in passing to examine them more closely, connecting threads from different parts of the history in ways that suggested he was forming a picture rather than following a checklist.

Then he read the records. All of them. The previous semen analyses. The hormonal profiles. The IVF cycle reports — the stimulation data, the embryology summaries, the transfer records. He read them in silence, occasionally asking a clarifying question, for forty minutes.

At the end of this reading, he said something to Sarita and Deepak that no previous doctor had said to them in eight years of treatment.

He said: there are tests that have not been done.

Not: we have found the problem. Not: I know what is wrong. But: the investigation that was performed before your previous cycles was not complete — and before I can tell you whether there is something to be done, I need to know what those tests show.

Sarita described this statement as the most honest thing she had heard in eight years of medical consultations. Not hopeful — not a promise of success. But specific. A doctor who had identified that the map was incomplete, and who wanted to draw the rest of it before making any claims about where they were standing.


Part Four: What the Investigation Found

The investigation that followed over the next three weeks was the most thorough fertility assessment Sarita and Deepak had ever undergone.

For Sarita: a complete hormonal reassessment including thyroid function and thyroid antibodies — which revealed elevated anti-TPO antibodies that had never been tested before. A hysteroscopy — which had never been performed across two previous IVF cycles — which revealed a small submucosal fibroid at the posterior wall of the uterine cavity, not visible on any of the standard ultrasounds that had been performed across eight years of treatment. ERA testing — which revealed that her implantation window was displaced by twenty-four hours from the standard protocol timing, meaning that both previous embryo transfers had been performed a full day before her endometrium was receptive. An immunological panel — which revealed elevated natural killer cell activity, assessed through endometrial biopsy, consistent with the pattern of good embryos that repeatedly failed to implant.

For Deepak: sperm DNA fragmentation testing for the first time in eight years — which revealed a DFI of 31 percent, consistent with the pattern of fertilization occurring and embryos developing but developmental quality being compromised at the genetic level beneath the surface that morphological grading could see.

Five findings. Five specific, previously unidentified factors. Each of them present, almost certainly, throughout both previous IVF cycles and the eight years of treatment that preceded them.

Dr. Soni presented these findings to Sarita and Deepak in a consultation that lasted an hour and ten minutes. He explained each finding in plain language — what it was, what it meant mechanically, how it had likely contributed to the previous failures, and what addressing it would involve. He was direct about the complexity — five co-existing factors was a significant presentation — but also direct about the tractability. Each factor was addressable. The question was whether addressing all five simultaneously would be sufficient to produce a different outcome.

He did not promise that it would. He said that the previous cycles had failed without the investigation to identify why. The next cycle would fail or succeed with the most complete understanding of the biology that was currently available. That was the difference he could offer.

Sarita said that she cried in the car on the way home — not from grief this time, but from something she found difficult to name precisely. Relief was part of it. The confirmation that the problem had not been invisible or irrational or unfixable — it had been specific, and it had been missed, and now it had been found. And underneath the relief, something more cautious and more fragile: the beginnings of a hope that she was not yet ready to trust.


Part Five: The Treatment

The treatment plan was built entirely around the five findings.

The fibroid was removed first — a hysteroscopic myomectomy performed by Dr. Soni, a thirty-minute procedure that left the uterine cavity clear for the first time in years, possibly for the first time since the fibroid had developed. Sarita was given time to recover and for the endometrium to regenerate before any further steps were taken.

Deepak's antioxidant pre-treatment — CoQ10, vitamin C, vitamin E, zinc, selenium — was initiated for a twelve-week period before the planned egg collection, to reduce the oxidative stress driving his elevated sperm DNA fragmentation. A repeat DFI at the end of this period showed reduction to 22 percent — still slightly elevated, but significantly improved. The decision was made to use testicular sperm for fertilization — TESA — to further minimize DNA fragmentation in the sperm used for ICSI.

Sarita's thyroid antibodies were addressed through levothyroxine supplementation, bringing her TSH to the fertility-specific optimal level below 2.5 mIU/L. Low-dose prednisolone was initiated for natural killer cell modulation, with careful monitoring.

The stimulation cycle was designed around Sarita's current hormonal profile — a modified antagonist protocol with a starting dose calibrated to her current AMH and her response history from previous cycles. Monitoring was careful and responsive — doses adjusted at each visit based on what the ultrasound showed rather than on a fixed schedule.

Six eggs were retrieved. Four were mature. Three fertilized using ICSI with testicular sperm. Two reached blastocyst stage on day five. Both were frozen. PGT-A testing confirmed that one of the two blastocysts was euploid.

The frozen embryo transfer was prepared with careful endometrial priming, Doppler monitoring of uterine blood flow, and transfer timing calibrated to the ERA finding — twenty-four hours later than the standard protocol, aligned precisely with Sarita's personalized implantation window.

One euploid embryo. Transferred at the time her ERA confirmed her endometrium was receptive, into a cavity cleared of the fibroid, in a body whose immunological environment had been modified and whose thyroid function had been optimized.


Part Six: The Wait

Sarita described the fourteen days after the embryo transfer as unlike any two-week wait she had experienced before.

This was not because the anxiety was less — it was not. The anxiety of the two-week wait does not diminish with clinical preparation or diagnostic thoroughness. Hope and fear coexist in that period in proportions that no amount of clinical evidence can fully alter.

What was different, she said, was the quality of what she was waiting to find out. In previous cycles, she had been waiting to see whether an embryo with unknown chromosomal content, transferred at a time that was assumed rather than confirmed to be correct, into a uterus that had never been fully examined, would implant. The uncertainty had extended in every direction — there were too many unknown variables.

This time, the known variables outnumbered the unknown ones. The embryo was chromosomally normal — confirmed. The transfer timing was personalized — confirmed. The uterine cavity was clear — confirmed. The sperm DNA was as intact as the available interventions could make it — confirmed. The immunological environment had been modified — as confirmed as that imprecise science allows.

What she was waiting to find out was whether the remaining unknown — the fundamental biological contingency of implantation, which even the most thorough clinical preparation cannot fully control — would resolve in their favor.

On the fourteenth day after the transfer, Sarita took the blood test at a local diagnostic center near her home, as Dr. Soni's team had instructed. The result was transmitted to Metro IVF before it reached her.

Dr. Soni called her directly.

The hCG was positive.


Part Seven: The Delivery Room

The pregnancy that followed was not uncomplicated — Sarita experienced first-trimester anxiety that was, she said, almost physically present, a constant companion that did not fully relax until the second trimester brought the reassurance of a growing, moving, consistently developing child within her.

She spoke to the Metro IVF team throughout the first trimester — not because clinical intervention was frequently needed, but because the reassurance of knowing that the team who had designed her treatment was available for questions was, during those months, something she needed and valued.

At twenty weeks, the anatomy scan showed a normally developing female fetus. Sarita said she looked at the scan image for a long time after the sonographer handed her the printed copy — at the specific, detailed, unmistakably human form on the page — and thought about the eight years of treatment and the consultation in Ambikapur and the phone call Deepak had made without telling her, and about all the things that had needed to be found and addressed before this image had become possible.

She delivered at thirty-eight weeks and four days. Normal vaginal delivery. Three kilograms and four hundred grams. A daughter.

In the delivery room, after the baby had been placed on Sarita's chest and before the particular exhausted euphoria of those first minutes had settled into anything coherent enough to be called thought, she said one thing. She said it quietly, to herself as much as to Deepak.

She said: they found it.

Not a reference to any specific finding. Not to the fibroid or the ERA or the sperm DNA or the antibodies. A reference to the whole of it — the investigation that had finally looked behind the door that eight years of treatment had kept closed. The looking that had changed everything.


What Sarita's Story Is For

Sarita asked us to share her story for one reason — the same reason every patient who gives us permission to tell their story gives.

Because somewhere in Chhattisgarh, or in Jharkhand, or in any of the districts and towns and villages whose residents find their way to Metro IVF, there is a woman who is where Sarita was before the phone call that changed everything. Who is carrying the weight of years of unexplained infertility and failed treatment with the practiced composure of someone who has learned not to show it. Who has almost stopped believing that a different outcome is possible.

And who has not yet made the phone call.

This story is for her.


Your Next Step

If any part of Sarita's story is your story — if you have been through years of treatment without a satisfying explanation, or cycles of IVF that produced good embryos and no pregnancy, or a grief that has become familiar enough to feel permanent — the first step is a consultation with Dr. Ashish Soni at Metro IVF in Ambikapur.

Bring everything. Every report. Every cycle summary. Every test result from every clinic. Dr. Soni will read all of it — carefully, completely, without rushing. He will identify what has not been investigated. He will conduct the evaluation that your case requires. And he will tell you, honestly and specifically, what he finds.

The door that was closed without anyone looking behind it properly may have an answer behind it.

The only way to know is to look.


Metro IVF Test Tube Baby Center Ambikapur, Chhattisgarh metrofertility.in Led by Dr. Ashish Soni — North India's First Fertility Super Specialist

From despair to the delivery room. The investigation that changes everything is available in Ambikapur. Book your consultation with Dr. Soni today.

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